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To make someone feel sad or upset
Synonyms
upset
verb [T] /ʌpˈset/
1
to make someone feel sad, worried, or angry 使难过;使烦恼;使生气

I'm sorry, I didn't mean to upset you. 对不起,我不是故意要惹你生气。

People were upset by Hansen's rude remarks. 人们被汉森粗鲁的言辞激怒了。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
wound
verb [T] /wuːnd/
2
to hurt someone's feelings by doing or saying something unpleasant (在感情上)使受创伤,伤害

Her remark had deeply wounded him. 她的话深深刺伤了他。

A string of rejections had really wounded his pride. 一连串的拒绝确实伤害了他的自尊心。

 Synonyms and related words
To insult or offend someone: insult, offend, wound...
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
disturb
verb [T] /dɪˈstɜː(r)b/
2
to upset and worry someone a lot 使烦恼;使心神不安

Ministers declared themselves profoundly disturbed by the violence. 部长们宣布他们对这一暴行深感不安。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
depress
verb [T] /dɪˈpres/
1
if something depresses you, it makes you feel unhappy and disappointed, and makes you want to stop trying to achieve things 使沮丧;使灰心丧气

Losing my job depressed me even further. 失去工作使我更加沮丧。

It depresses me to see all that time being wasted. 看到所有的时间都白白浪费使我灰心丧气。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
distress
verb [T] /dɪˈstres/
to make someone feel very unhappy, worried, or upset 使苦恼;使悲伤;使忧虑

It distresses him to think that he has no hope of changing things. 想到无法改变一切,他很苦恼。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
devastate
verb [T] [usually passive] /ˈdevəˌsteɪt/
2
to make someone feel very shocked and upset 使十分震惊;使心神不定

Mary's sisters were devastated by her disappearance. 玛丽的姐妹们对她的失踪感到非常震惊。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
dismay
verb [T] /dɪsˈmeɪ/
to make someone very worried, disappointed, or sad 使不安;使失望;使难过

What dismayed me most about their behaviour was their rudeness. 他们的行为最让我失望的是他们的粗鲁。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
stab
verb /stæb/
2a
if someone's words stab you, they make you feel suddenly very sad or afraid (话语)刺伤,刺痛

His words stabbed her to the heart. 他的话刺痛了她的心。

 Synonyms and related words
To make someone afraid or frightened: frighten, alarm, scare...
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
worry
verb /ˈwʌri/
1a
[T] to make someone feel nervous and upset 使担心;使焦虑

What worries me most is the possibility of complete failure. 最让我忧虑的是可能会彻底失败。

worry yourself about something :

Tell them not to worry themselves about the financial position. 告诉他们不用担心财务情况。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
hang over
phrasal verb [T]
[hang over someone/something] if something hangs over you, you worry about it or feel upset about it 威胁;使忧虑;使烦恼

The threat of homelessness hangs over hundreds of families. 成百上千的家庭面临着无家可归的威胁。

A sense of doom hung over the town. 一种末日将要来临的可怕预感笼罩着全镇。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
More Synonyms
agitate
verb /ˈædʒɪteɪt/
3
[T] to make someone worried or upset 使焦虑;使躁动不安
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
assail
verb [T] /əˈseɪl/
1
to make someone feel worried or upset 使担心;使苦恼

He was assailed by doubts. 他被疑问困扰着。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
bother
verb /ˈbɒðə(r)/
3
[T] to make someone feel worried or upset 使担心;使苦恼

There was something about him that really bothered her. 他的一些事使她伤脑筋。

it bothers someone that/when :

Does it bother you that people think you're older than him? 人们觉得你比他老,你会为此烦恼吗?

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
break someone's heart
phrase
1
to upset someone very much, especially by letting them know that you do not love them. You can also say that someone's heart breaks or that they have a broken heart (尤指因告知自己对其并无爱意而)使某人心碎

Friends and relatives said she died of a broken heart.

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
2

it breaks someone's heart

spoken used for saying that something upsets someone very much 某事使某人心碎
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
bring someone back down to earth (with a bump)
phrase
to make someone suddenly remember the real situation or things that they have to do, after they have been so happy or excited that they forgot 使某人(在激动或欣喜之后)回到现实;使某人清醒过来

Losing the match brought them back down to earth with a bump.

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
burst someone's bubble
phrase
to end someone's happiness by making them realize what is happening 使某人的幻想破灭

I hate to burst your bubble, but I don't think he remembers you. 我不想打破你的幻想,但是我想他不记得你了。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
crush
verb /krʌʃ/
3
[T] [usually passive] to make someone feel disappointed, embarrassed, or upset 使失望(或尴尬、烦恼)

He would be crushed by another rejection.

 Synonyms and related words
To make someone feel ashamed or embarrassed: embarrass, humiliate, shame...
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
disgust
verb [T] /dɪsˈɡʌst/
1
if something disgusts you, it is so bad or immoral that it makes you angry and upset 使生气;使愤慨

Your whole attitude disgusts me. 你的整个态度令我气愤。

 Synonyms and related words
To make someone angry or annoyed: annoy, provoke, anger...
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
drag down
phrasal verb [T]
2
to make someone feel unhappy or less hopeful 使不高兴;使垂头丧气

I don't mean to drag you down with all my problems. 我不想让我的这些问题把你搞得很不高兴。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
drive someone mad
phrase informal
to make someone feel extremely angry or upset 使某人非常生气(或心烦意乱)

Please stop making that banging noise – it's driving me mad! 请不要砰砰乱敲,烦死我了!

He drives me mad with his constant criticizing. 他不断地批评我,把我气疯了。

 Synonyms and related words
To make someone angry or annoyed: annoy, provoke, anger...
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
eat away at
phrasal verb [T]
to make someone feel more and more unhappy or worried 使(某人)愈来愈烦忧

You could see that jealousy was eating away at her. 你可以看出来嫉妒正令她寝食难安。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
excite
verb [T] /ɪkˈsaɪt/
1a
to make someone feel lively, nervous, or upset 使紧张;刺激

We were warned by the doctors not to excite him. 医生警告我们不要刺激他。

 Synonyms and related words
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
faze
verb [T] informal /feɪz/
to make someone feel confused, shocked, or upset 打扰;使担忧;烦扰
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
 Synonyms and related words
To make someone unable to concentrate or think clearly: discombobulate, confuse, distract...
get down
phrasal verb
1
[T] [get someone down] informal to make someone feel sad or lose hope 使悲伤;使沮丧

Doing the same thing every day can get you down. 整天都做同样的事情会让人很沮丧。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
get to
phrasal verb [T] informal
1
[get to someone] to annoy or upset someone 使生气;使烦恼

After a while his teasing started to get to me. 过了一会儿,他的挑逗就开始让我不舒服了。

 Synonyms and related words
To make someone angry or annoyed: annoy, provoke, anger...
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
gnaw at
phrasal verb [T]
[gnaw (away) at someone] if something gnaws at you, you keep worrying about it or feeling upset about it 不停地困扰(某人)
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
grieve
verb /ɡriːv/
2
[T] formal to upset someone 使伤心

It grieves me to see her like this. 看到她这样我很伤心。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
haunt
verb [T] /hɔːnt/
2
to make someone feel worried and upset for a long time 萦绕在…心头;缠扰

Images from the war still haunt him. 战争的影像仍萦绕在他的脑海里。

Caroline was haunted by a fear of cancer. 卡罗琳因担心患癌症而老是提心吊胆。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
hurt
verb /hɜː(r)t/
3
[I/T] to cause someone emotional pain (给…)造成精神痛苦;伤害(感情)

I never meant to hurt your feelings. 我从来不想伤害你的感情。

His cold behaviour hurt her deeply. 他冷淡的态度深深地伤害了她。

it hurts that :

It really hurts that you'd believe her instead of me. 你宁愿相信她而不相信我,这实在让人伤心。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
kick someone in the teeth
phrase informal
to upset someone, or to make them feel disappointed, especially when they are trying hard to achieve something (尤指在其竭力争取某事物时)使某人心烦意乱,使某人大失所望
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
knock out
phrasal verb [T]
5
[knock someone out] informal to make someone feel very shocked or upset 使(某人)震惊;使(某人)不安
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
knock someone for six/knock someone sideways
phrase informal
to make someone feel very shocked or upset 使某人吃惊;使某人不安
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
knock the stuffing out of someone
phrase
to make someone physically or mentally weak 使某人身体变弱;使某人气馁

She had a bad cold which really knocked the stuffing out of her.

 Synonyms and related words
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
lie heavy on someone
phrase formal
to make someone feel unhappy 令某人觉得不开心

Feelings of guilt lay heavy on him. 内疚感令他无法快乐起来。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...

mess with

or mess around with

[T] informal
  1. 1
    [mess with someone] to make someone angry, or to argue with them 使生气;使争吵

    I wouldn't mess with her if I were you. 如果我是你我不会去惹她。

     Synonyms and related words
     Synonyms and related words
    To make someone angry or annoyed: annoy, provoke, anger...
  2. 2
    [mess with something] to become involved with something that is dangerous 沾染(有害之物)

    A lot of the kids had been messing with drugs. 许多小孩沾染上了毒品。

     Synonyms and related words
    To take risks: risk, dare, jeopardize...
  3. 3
    mess with someone's head very informal to seriously upset someone or make them confused 使某人心烦意乱;使某人困惑不解
     Synonyms and related words
    To make someone feel sad or upset: upset, wound, disturb...
     Synonyms and related words
    To make someone unable to concentrate or think clearly: discombobulate, confuse, distract...
move
verb /muːv/
7
[T] to affect someone emotionally, especially by making them feel sad and serious 感动;打动

You can't fail to be moved by the plight of these people. 你一定会被这些人的困境所触动。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
nauseate
verb [T] /ˈnɔːzieɪt/ /ˈnɔːsieɪt/
2
to make someone feel upset 使感到厌恶;使心烦

It nauseates me to think that he has profited from this. 想到他从中谋取利益我就感到厌恶。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
oppress
verb [T] [often passive] /əˈpres/
2
to make someone feel very worried or unhappy 使烦恼
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
overcloud
verb [T] mainly literary /ˌəʊvə(r)ˈklaʊd/
to spoil an event by making everyone sad or worried 使悲伤;使忧郁;使扫兴
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
pain
verb [T] /peɪn/
1
to make someone feel very upset or unhappy 使痛苦;使苦恼

It was clear the subject pained him. 显然这个问题使他感到很苦恼。

it pains someone to do something :

It pained her to think that they would never talk to each other again. 一想到他们将再也不能交谈,她感到十分痛苦。

it pains someone that :

It pains me that we're such hypocrites about it. 我们在这件事上如此虚伪,我感到很痛苦。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
ruffle
verb [T] /ˈrʌf(ə)l/
2
to make someone feel upset 使不平静;打扰;扰乱

Don't let him ruffle you. 别让他打扰你。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
sadden
verb [T] formal /ˈsæd(ə)n/
to make someone feel sad 使悲伤;使伤心;使难过

The events of the past week have shocked and saddened us all. 上个星期的事情让我们大家都很震惊和难过。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
screw up
phrasal verb
4
[T] informal to make someone feel so upset or confused that their whole personality is affected, often permanently (常指永久性地)使紧张,使精神不正常

Divorce doesn't have to screw your children up. 离异并不一定非得把孩子们弄得精神紧张。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
sting
verb /stɪŋ/
2a
to make someone feel angry and upset 使生气;使心烦

She was stung by her father's criticism. 她因父亲的批评而感到心烦意乱。

 Synonyms and related words
To make someone angry or annoyed: annoy, provoke, anger...
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
stir
verb /stɜː(r)/
2

stir

or

stir up

[T] to make someone feel upset or angry 激起,激发(不安或愤怒)
stir anger/hatred/fears :

This murder has stirred a lot of ill feeling in the community. 这次谋杀在社区里引发了很多不良情绪。

The latest economic figures have stirred fears of growing inflation. 最新的经济统计数字引起了人们对愈来愈严重的通货膨胀的恐惧。

 Synonyms and related words
To make someone angry or annoyed: annoy, provoke, anger...
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
tear apart
phrasal verb [T]
1
to make someone feel very sad, upset, or worried 使…难过;使…不安;使…烦恼

It just tears me apart to see you suffering like this. 看你这么痛苦,真叫我难受。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
tear someone's heart out/tear at someone's heart
phrase literary
to make someone feel very sad or upset 使某人非常伤心(或不安、心痛)
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
tear up
phrasal verb [T]
4
[tear someone up] to make someone feel very unhappy or upset 使(某人)难过;使(某人)不安

It tears me up to leave you. 离开你真让我难过。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
tip someone over the edge/brink
phrase
to make someone feel so unhappy that they cannot deal with their life or a situation any longer 使某人受不了;使某人难过得不得了

Losing the business was what finally tipped him over the edge.

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
torture
verb [T] /ˈtɔː(r)tʃə(r)/
2
to make someone feel extremely worried or upset about something 使…极为担心(或苦恼)

Don't torture yourself by thinking about the money. 别再想着那笔钱折磨你自己了。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
touch a nerve
phrase
to upset someone, or to make them angry 使人恼怒;让人生气

Eileen's innocent remark seemed to have touched a nerve. 艾琳天真无知的话似乎有点让人生气。

 Synonyms and related words
To make someone angry or annoyed: annoy, provoke, anger...
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
touch/hit a raw nerve
phrase
to upset someone by referring to something that they are sensitive about 伤害到感情;触及到痛处

His criticisms clearly touched a raw nerve. 他的批评明显地触及到了痛处。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
traumatize
verb [T] [usually passive] /ˈtrɔːmətaɪz/
to make someone feel very upset, afraid, or shocked 使忐忑不安;使极为恐惧;使大吃一惊;使十分痛苦

Many children are traumatized by their parents' divorce. 父母的离异给许多孩子造成极大痛苦。

 Synonyms and related words
To make someone afraid or frightened: frighten, alarm, scare...
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
unhinge
verb [T] /ʌnˈhɪndʒ/
to make someone upset or mentally ill 使烦恼;使精神失常
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
unsettle
verb [T] /ʌnˈset(ə)l/
to make someone feel nervous, confused, or upset 使紧张;使困惑;使烦恼

The experience unsettled her profoundly. 这一经历使她心绪极为不宁。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
wind up
phrasal verb
4
[T] informal to make someone angry or upset 使生气;使烦恼

Please don't wind him up – he causes me enough trouble. 请不要惹他生气,他给我带来的麻烦够多的了。

 Synonyms and related words
To make someone angry or annoyed: annoy, provoke, anger...
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
wipe the smile/grin off someone's face
phrase informal
to stop someone who is annoying you from feeling so happy or pleased 让某人不再高兴;让某人不再得意

We won't be promoting Larry. That should wipe the grin off his face. 我们不会提拔拉里,那样他就不会再得意了。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
Others

dishearten

verb [T]
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
knock someone for a loop
phrase informal
to make someone feel very shocked or upset 使某人吃惊;使某人不安
 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...
 Synonyms and related words
touch/strike/hit a raw nerve
phrase
to upset someone by referring to something that they are sensitive about 伤害到感情;触及到痛处

His criticisms clearly touched a raw nerve. 他的批评明显地触及到了痛处。

 Synonyms and related words
To make someone feel sad or upset: upset, wound, disturb...

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